09/2024:

• i2b2 release 1.8.1a available! (includes fix for breakdown queuing for SQL server and Postgres)
• Data Exporter extension for i2b2
• ACT Version 4.1 Ontology
• i2b2 on OMOP for Postgres database
• New webclient with Admin Console
• Digital Twin Bundle

Accrual to Clinical Trials

The Accrual to Clinical Trials (ACT) project goal is to create a federated network of National Clinical and Translational Science Award (CTSA) Consortium institutions to significantly increase participant accrual to the nation's highest priority clinical trials.

Multi-fact Table

The multi-fact table project is a new feature introduced in 1.7.09 that enables the i2b2 to query more than one fact table. This new feature empowers the i2b2 to adapt to the needs of such projects as the Patient Centered Outcome Research Institute (PCORI) network and the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM). It can also be used for sites that want to be able to query both genomic and phenotype data but don't want the data to reside in a single table.

OMOP

The legacy i2b2 data model is comprised of a central fact table (observation_fact) surrounded by multiple dimension tables (star schema). In the Observation Medical Outcomes Partnership (OMOP) Clinical Data Model (CDM) rather than a central fact table, we have a collection of them distinguished by domain: procedures, condition, drug, measurement, observation, etc. In this project, we modify the CRC to run queries against multiple domain fact tables as dictated by the metadata.

RDF to i2b2 Conversion

Synthea data in i2b2

Synthea synthetic data can now be loaded into i2b2 for testing. A 63k sample of SyntheticMass patients is available for download.

i2b2 on Genomics Data

This community project extends the current i2b2 query functionality by providing the ability to query for genotyped subjects by specific annotations related to genetic variants. Also, new query widgets have been built in the i2b2 web client that leverages existing i2b2 infrastructure for querying large strings of text stored in the observation_blob field of the observation_fact table.

See All Community Projects

Important links:

• SHRINE Approved

  1.7.13 Release and Classic webclient downloads are available at i2b2 Software Downloads Links - All Releases

• i2b2 tranSMART Working Groups
• New Project: i2b2 on OMOP
• New Project:  i2b2 on Genomics Data

Older Announcements:

i2b2 Log4j Vulnerability Update

None of the versions of i2b2 are using the affected (vulnerable) version of Log4j. For versions prior to 1.7.13, a patch is available to remove the features in Log4j with security flaws. i2b2 1.7.13 has been upgraded to the latest version of Log4J.

Consortium for Clinical Characterization of Covid-19 by EHR (4CE)

4CE is an international consortium for electronic health record (EHR) data-driven studies of the COVID-19 pandemic. The goal of this effort—led by the i2b2 international academics users group—is to inform doctors, epidemiologists and the public about COVID-19 patients with data acquired through the health care process.

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