• i2b2 is an open-source clinical data warehousing and analytics research platform used at over 250 locations worldwide. i2b2 enables sharing, integration, standardization, and analysis of heterogenous data from healthcare and research. 
• The i2b2 Community is a life-sciences-focused open-source, open-data community. This wiki is the central place for the i2b2 Community to communicate and share projects with other users. Here you will find the latest information on the i2b2 Software, what others in the community are doing, and find resources to help answer any questions you may have about the i2b2. 
• i2b2 is part of the i2b2 tranSMART Foundation, which brings together an NIH-funded enterprise clinical research platform (i2b2) and pharma-developed software for translational research studies (tranSMART).

Documentation	Get Software	Announcements
Getting Started Installation Guide Upgrade Guide Videos and Tutorials NEW - i2b2 Common Data Model Guide NEW - Bundle Install Guides (beta version!)  For Developers Server-side Messaging Server Architecture Server-side Design Web Client Design Release Notes For End Users Web Client Help Workbench User Guide	Project Management Ontology Management Data Repository (CRC) File Repository (CRC) Workflow Framework Identity Management i2b2 Web Client Application i2b2 Workbench Application               i2b2 Hive Older, unsupported add-ons are on the Archived Optional Components page. Project Management Core Server Side i2b2 Cell This cell is used to provide user authentication and manage group and role information. It also keeps track of what cells are part of the hive. Installation Guide Messaging Guide Design Document Go to Download Ontology Management Core Server Side i2b2 Cell This cell manages the terminology and knowledge information typically used in the hive. It is contacted for, or distributes knowledge to, cells during most of the hives transactions. Installation Guide Messaging Guide Design Document Architecture Document Go to Download Data Repository (CRC) Core Server Side i2b2 Cell This cell holds the phenotypic and genotypic data of the hive in a structured format. Data queries and visualizations are available through this cell. Installation Guide Messaging Guide Design Document Architecture Document Plugin Analysis Document Go to Download Workplace Framework Core Server Side i2b2 Cell This cell is used to process information in steps through various parts of the hive. Most processed information will come to reside in the Data Repository Cell or as a display to the user. Installation Guide Messaging Guide Design Document Architecture Document Go to Download i2b2 Web Client The i2b2 Web Client is a collection of client-side components designed as an YUI AJAX-based plug-ins that communicate with i2b2 Cells and allow the investigator to query and display the data of the hive. Install Guide Project Request Guide Go to Download i2b2 Hive The Hive is a collection of software modules that create a system to allow the use of patient data for research. i2b2 Hive Introduction i2b2 Message Wrapper i2b2 Patient Data Object i2b2 Workbench The i2b2 Workbench is a collection of client-side components designed as Eclipse-based java plug-ins that communicate with i2b2 Cells and allow the investigator to query, analyze, and display the data of the hive, generally in greater depth than the web client. Installation Guide Tutorial Document Developer's Guide Go to Download Go to Download Source File Repository Core Server Side i2b2 Cell This cell holds large files of data including radiological images and genetic sequences. The files are generally referenced from the Data Repository Cell. Installation Guide Messaging Guide Architecture Document Go to Download Identity Management Core Server Side i2b2 Cell This cell is used to manage a patient's protected health information in a manner consistent with the HIPAA privacy rule. Patient data is available only as a HIPAA defined "Limited Data Set" to most of the hive. Installation Guide Messaging Guide Design Document Architecture Document Go to Download Download The source code files for the i2b2 Core Hive Cells, i2b2 Workbench and Web Client are listed below. The i2b2 Source is a collection of both client and server source code and can be used to build the i2b2 Server and Workbench from scratch. Demo data, current documentation, and VMware i2b2 server installed on CentOS can also be downloaded. Version: 1.7.12 Release Date: December 27, 2019 License: Mozilla 2 Open Source License You are viewing all available releases of i2b2. Click here to view the latest release of i2b2. Version 1.8.1  SHRINE Approved Software Version i2b2 Binary Download  1.8.1 (June 2024) Download Full Download Upgrade i2b2 Core Server Source Code 1.8.1 (June 2024) Download i2b2 Core Data Source Code 1.8.1 (June 2024) Download i2b2 Web Client 1.8.1 (June 2024) Download i2b2 Documentation 1.8.1 (June 2024) Release Notes Release Notes PDF Upgrade Guide Install Guide i2b2 VMWare Server/Client Demo 1.8.1 Coming Soon i2b2 Docker Demo (unofficial) 1.8.0  Installation Guide i2b2 Workbench 2.0.01 (October 17, 2017) Download Version 1.8.0 Software Version i2b2 Binary Download  1.8.0 (December 2023) Download Full Download Upgrade i2b2 Core Server Source Code 1.8.0 (December 2023) Download i2b2 Core Data Source Code 1.8.0 (December 2023) Download i2b2 Web Client 1.8.0 (December 2023) Download i2b2 Documentation 1.8.0 (December 2023) Release Notes Release Notes PDF Upgrade Guide Install Guide i2b2 VMWare Server/Client Demo 1.8.0 Download i2b2 Docker Demo (unofficial) 1.8.0  Installation Guide i2b2 Workbench 2.0.01 (October 17, 2017) Download Version 1.7.13 SHRINE Approved Released June 2022 under the Mozilla 2 Open Source License Software Version i2b2 Binary Download  1.7.13 (June, 2022) Download Full Download Upgrade i2b2 Core Server Source Code 1.7.13 (June, 2022) Download i2b2 Core Data Source Code 1.7.13 (June, 2022) Download i2b2 Web Client 1.7.13 (June, 2022) Download i2b2 Documentation 1.7.13 (June, 2022) Release Notes Release Notes PDF Upgrade Guide Install Guide i2b2 VMWare Server/Client Demo 1.7.13 (Coming Soon) Download i2b2 Docker Demo (unofficial) 1.7.13 (June, 2022) Docker Instructions i2b2 Workbench 2.0.01 (October 17, 2017) Download Version 1.7.12a  SHRINE Approved Released May 2020 under the Mozilla 2 Open Source License i2b2 Source Code 1.7.12a Software Version i2b2 Core Server Source Code 1.7.12a (May, 2020) Download i2b2 Core Data Source Code 1.7.12a (May, 2020) Download i2b2 Web Client 1.7.12a (May, 2020) Download i2b2 VMWare Server/Client Demo 1.7.12a (May, 2020) Download i2b2 Docker Demo (unofficial) 1.7.12a (May, 2020) Docker Instructions i2b2 Workbench 2.0.01 (October 17, 2017) Download Version 1.7.12  Deprecated Released December 2019 under the Mozilla 2 Open Source License i2b2 Source Code 1.7.12 Software Version i2b2 Core Server Source Code 1.7.12 (December, 2019) Download i2b2 Core Data Source Code 1.7.12 (December, 2019) Download i2b2 Web Client 1.7.12 (December, 2019) Download i2b2 VMWare Server/Client Demo 1.7.12 (December, 2019) Download i2b2 Workbench 2.0.01 (October 17, 2017) Download Version 1.7.11 Released February 27, 2019 under the Mozilla 2 Open Source License i2b2 Source Code 1.7.11 Package Version Description File Size Download i2b2core-src-1711.zip 1.7.11 Core Source Code Server - a collection of both client and server Java source code and can be used to build the i2b2 Server and Workbench from scratch 56 MB Download i2b2webclient-1711.zip 1.7.11 Web Client Source - HTML/Javascript source code for the i2b2 web client 5 MB Download i2b2createdb-1711.zip 1.7.11 i2b2 Data for Oracle, PostgreSQL, and SQL Server - scripts to setup your i2b2 database including demo data 27 MB Download Version 1.7.10 Released April 30, 2018 under the Mozilla 2 Open Source License i2b2 Source Code 1.7.10 Package Version Description File Size Download i2b2core-src-1710.zip 1.7.10 Core Source Code Server - a collection of both client and server Java source code and can be used to build the i2b2 Server and Workbench from scratch 56 MB Download i2b2webclient-1710.zip 1.7.10 Web Client Source - HTML/Javascript source code for the i2b2 web client 5 MB Download i2b2createdb-1710.zip 1.7.10 i2b2 Data for Oracle, PostgreSQL, and SQL Server - scripts to setup your i2b2 database including demo data 27 MB Download i2b2 VMWare 1.7.10 Package Version Description File Size Download i2b2vmware-1710.zip 1.7.10 VMware Core Image - Complete VMware i2b2 server installed on CentOS. Only tested on VMWare Fusion and Player. When you have run the image, please use the following login for CentOS: demo (or root) / demouser 2.6 GB Download vmware_install_guide_17.pdf 1.7.10 VMWare Installation Guide 1 MB Download Version 1.7.09C  SHRINE Approved Released January 12, 2018 under the Mozilla 2 Open Source License  i2b2 Source Code 1.7.09C Package Version Description File Size Download i2b2core-src-1709c.zip 1.7.09C Core Source Code Server - a collection of both client and server Java source code and can be used to build the i2b2 Server and Workbench from scratch 56 MB Download i2b2webclient-1709c.zip 1.7.09C Web Client Source - HTML/Javascript source code for the i2b2 web client 5 MB Download i2b2createdb-1709c.zip 1.7.09C i2b2 Data for Oracle, PostgreSQL, and SQL Server - scripts to setup your i2b2 database including demo data 27 MB Download i2b2 VMWare 1.7.09C Package Version Description File Size Download i2b2vmware-1709c.zip 1.7.09C VMware Core Image - Complete VMware i2b2 server installed on CentOS. Only tested on VMWare Fusion and Player. When you have run the image, please use the following login for CentOS: demo (or root) / demouser 2.6 GB Download Older Optional Components These are optional components that can be used to enhance your i2b2 and released under the Mozilla 2 Open Source License. They are no longer officially supported. i2b2 Optional Components Package Version Description File Size Download i2b2PFT-src-13.zip 1.3 PFT Client/Server Source 35 MB Download i2b2NLP-src-10.zip 1.0 NLP Client/Server Source 5 MB Download CorrelationAnalysis-client-src-10.zip 1.0 Correlation Analysis Client Source 3.5 MB Download HPC-src-10.zip 1.0 HPC Client/Server Source 6.7 MB Download i2b2crcplugin-patientcount-17.zip 1.7 CRC Patient Count Plugin 38 MB Download i2b2tableview-14.zip 1.4 Table View Plugin 26 MB Download i2b2DerivedDataMarts-src-14.zip 1.4 Derived Data Marts 97 KB Download i2b2exportdata-15.zip 1.5 Export Data Plugin 8.6 MB Download i2b2annotator-15.zip 1.5 Annotator Plugin 5.4 MB Download i2b2textanalyzer-15.zip 1.5 Text Analyzer Plugin 638 KB Download i2b2importdata-15.zip 1.5 Import Data Plugin 16 MB Download Software Version i2b2 Core Server Source Code 1.7.11 (March 6, 2019) Download i2b2 Core Data Source Code 1.7.11 (March 6, 2019) Download i2b2 Web Client 1.7.11 (March 6, 2019) Download i2b2 Documentation 1.7.11 (March 6, 2019) Release Notes Upgrade Guide Install Guide i2b2 VMWare Server/Client Demo 1.7.11 (March 6, 2019) Download i2b2 Workbench 2.0.01 (October 17, 2017) Download	What's New in i2b2? COMING SOON New Webclient Documentation IN DEVELOPMENT i2b2 Release 1.7.12, expected September 2019 i2b2 Release 1.7.11 now available! New security features and much more! (Upgrade server to 1.7.11) Important links: i2b2 tranSMART Working Groups New Project: i2b2 on OMOP New Project:  i2b2 on Genomics Data

New i2b2 Community Projects

Accrual to Clinical Trials

The Accrual to Clinical Trials (ACT) project goal is to create a federated network of National Clinical and Translational Science Award (CTSA) Consortium institutions to significantly increase participant accrual to the nation's highest priority clinical trials.

Multi-fact Table

The multi-fact table project is a new feature introduced in 1.7.09 that enables the i2b2 to query more than one fact table. This new feature empowers the i2b2 to adapt to the needs of such projects as the Patient Centered Outcome Research Institute (PCORI) network and the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM). It can also be used for sites that want to be able to query both genomic and phenotype data but don't want the data to reside in a single table.

OMOP

The legacy i2b2 data model is comprised of a central fact table (observation_fact) surrounded by multiple dimension tables (star schema). In the Observation Medical Outcomes Partnership (OMOP) Clinical Data Model (CDM) rather than a central fact table, we have a collection of them distinguished by domain: procedures, condition, drug, measurement, observation, etc. In this project, we modify the CRC to run queries against multiple domain fact tables as dictated by the metadata.

i2b2 Workbench

The i2b2 Workbench is one of two i2b2 clients available to the i2b2 community. It is a collection of client-side components that communicate with i2b2 cells and help aggregate their functionality in the the i2b2 Hive. Each workbench component is designed as an Eclipse-based plug-in that interacts with a hive cell; collectively these plugins provide a cohesive entity to tie all the i2b2 cells together.

i2b2 on Genomics Data

This community project extends the current i2b2 query functionality by providing the ability to query for genotyped subjects by specific annotations related to genetic variants. Also, new query widgets have been built in the i2b2 web client that leverages existing i2b2 infrastructure for querying large strings of text stored in the observation_blob field of the observation_fact table.

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