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The Cincinnati Children's Hospital Medical Center (CCHMC) i2b2 team has extended i2b2 to create an enhanced patient registry and an associated web-based toolkit.  It provides the necessary functionality in a modular fashion, allowing users to choose the capabilities that are appropriate for their project.?he   The enhanced registry architecture includes linkage to the EHR and an application layer that allows the development of functionality to support quality improvement and comparative effectiveness research.  There are capabilities for data collection to capture information that is not collected in an EHR, as well as mechanisms for reporting and visualization.

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