Developers Getting Started With i2b2
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A Note on Using Active Directory in SQLServer

If you are using SQL Server, it is possible to use Active Directory accounts for the database users (i.e., Integrated Login). To enable this, replace

<connection-url>jdbc:sqlserver://localhost:1433</connection-url>

with 

<connection-url>jdbc:sqlserver://localhost:1433;IntegratedSecurity=true;Trusted_Connection=Yes</connection-url>