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Each of the current sites uses i2b2 and SHRINE to develop Comparative Effectiveness Research data discovery resources. The project evolved out of the i2b2 Cross-Institutional Clinical Translational Research project (CICTR) - a SHRINE-based federation of UC Davis, UC San Francisco and the University of Washington. The HOMERUN technical collaboration focusses on the policy, data aquisition and mapping processes, and is moving towards harmonizing necessary version-level implementation for local sites. HOMERUN uses the HOM mapper for concept translation. 

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