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For instance, diabetes mellitus is an endocrine disorder, which is a type of diagnosis. Aspirin is a non-steroidal anti-inflammatory drug, which is a type of drug.
What's the source of these concepts and domains? (Where do they come from?)
Typically, the concepts that make up domains are based on medical terminology standards. Some commonly used standards to represent basic structured clinical patient data collected in EHRs include:
| Data domains | Typical Standards |
| Demographics | HL7 Administrative |
| Diagnoses | ICD |
| Procedures | ICD, CPT, HCPCS |
| Medications | RxNorm + VA Classes hierarchy |
| Labs | LOINC |
| Vital Signs | LOINC |
- Medical terminology releases are not directly usable by i2b2
- Standardized I2b2 tables must be created for each desired medical terminology to make it usable within i2b2.
Do all i2b2 instances always have the same ontology?
No. Several i2b2 ontologies have been developed and are openly available for us. Any organization may also modify an existing ontology for it's own use, or develop a new ontology.
That may be the "demo" ontology, but it doesn't resemble the "ACT" ontology that our PI was showing us. How many different ontology trees does i2b2 have?
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